US Stock MarketDetailed Quotes

Ionis Pharmaceuticals (IONS)

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  • 73.270
  • -0.820-1.11%
Close Apr 24 16:00 ET
  • 73.270
  • 0.0000.00%
Post 19:24 ET
12.10BMarket Cap-30.79P/E (TTM)

Earnings

Revenue Breakdown

Financial Indicators

Income Statement

Balance Sheet

Cash Flow

Ionis Pharmaceuticals (IONS) Cash Flow

Quarterly+Annual
YOY yoy
Hide blank lines yoy
(FY)Dec 31, 2025
(Q4)Dec 31, 2025
(Q3)Sep 30, 2025
(Q2)Jun 30, 2025
(Q1)Mar 31, 2025
(FY)Dec 31, 2024
(Q4)Dec 31, 2024
(Q3)Sep 30, 2024
(Q2)Jun 30, 2024
(Q1)Mar 31, 2024
Operating Cash Flow (Indirect Method)
Cash flow from continuing operating activities
46.38%-268.58M
-18.57%-137.71M
-14.30%-131.44M
226.24%151.34M
-0.56%-150.78M
-62.90%-500.95M
-453.38%-116.14M
-5.47%-114.99M
-23.13%-119.88M
-11.90%-149.94M
Net income from continuing operations
15.97%-381.39M
-119.83%-229.39M
8.45%-128.61M
286.45%123.55M
-2.90%-146.94M
-23.92%-453.9M
-1,026.51%-104.35M
4.70%-140.48M
22.31%-66.27M
-14.86%-142.8M
Operating gains losses
-69.55%4.06M
42.84%17.14M
-12,868.58%-33.85M
397.70%18.86M
186.86%1.91M
99.79%13.33M
282.62%12M
-101.82%-261K
132.13%3.79M
-325.77%-2.2M
Depreciation and amortization
3.20%22.69M
39.38%7.34M
-18.04%4.5M
-2.24%5.45M
-4.49%5.4M
-2.26%21.99M
-6.15%5.27M
-1.75%5.49M
-1.93%5.58M
0.80%5.65M
Other non cash items
-21.50%27.13M
1.24%5.7M
-0.10%5.87M
-20.22%8.14M
-42.25%7.42M
15.41%34.56M
121.08%5.63M
44.16%5.87M
57.67%10.2M
-23.73%12.85M
Change In working capital
75.54%-51.22M
138.86%23.86M
36.01%-5.41M
69.71%-28.48M
9.55%-41.18M
-171.02%-209.39M
-572.70%-61.39M
-129.99%-8.46M
-197.89%-94.03M
17.24%-45.52M
-Change in receivables
367.42%26.13M
44.18%-41.45M
199.77%27.97M
41.80%-12.87M
-43.35%52.48M
107.76%5.59M
-265.93%-74.26M
108.15%9.33M
-59.38%-22.12M
696.95%92.64M
-Change in inventory
-169.65%-13.67M
118.36%926K
-887.82%-2.14M
-1,590.72%-13.48M
102.40%1.01M
-105.39%-5.07M
-545.58%-5.04M
382.29%271K
76.12%-797K
398.80%499K
-Change in payables and accrued expense
245.70%36.59M
-118.15%-9.45M
527.03%85.82M
138.72%28.9M
33.29%-68.67M
-218.68%-25.12M
7.48%52.04M
122.14%13.69M
-66.70%12.11M
-47.54%-102.95M
-Change in other current assets
-28.44%-33.21M
609.98%90.28M
-8,334.34%-100.95M
50.22%-10.17M
-211.93%-12.37M
23.42%-25.86M
-14.67%-17.7M
-10.58%1.23M
18.31%-20.43M
107.98%11.05M
-Change in other working capital
57.81%-67.05M
-0.20%-16.45M
51.13%-16.11M
66.77%-20.86M
70.86%-13.63M
-1,710.46%-158.94M
75.08%-16.42M
-131.87%-32.97M
-144.35%-62.79M
-2,237.95%-46.76M
Cash from discontinued investing activities
Operating cash flow
46.38%-268.58M
-18.57%-137.71M
-14.30%-131.44M
226.24%151.34M
-0.56%-150.78M
-62.90%-500.95M
-453.38%-116.14M
-5.47%-114.99M
-23.13%-119.88M
-11.90%-149.94M
Investing cash flow
Cash flow from continuing investing activities
-107.25%-277.78M
-714.99%-419.51M
126.80%91.34M
-292.26%-120.07M
123.98%170.46M
37.41%-134.03M
355.36%68.21M
-595.98%-340.8M
-10.16%62.45M
123.37%76.11M
Net PPE purchase and sale
-13.61%-51.44M
16.49%-21.29M
41.81%-5.27M
-97.39%-12.31M
-179.92%-12.58M
-90.21%-45.28M
-3,213.19%-25.5M
-322.98%-9.06M
48.10%-6.23M
57.10%-4.49M
Net intangibles purchase and sale
-11.44%-5.64M
46.41%-1.37M
-113.02%-1.66M
86.00%-1.96M
47.37%-651K
-20.96%-5.06M
-230.78%-2.55M
1,259.09%12.75M
-1,222.05%-14.03M
1.28%-1.24M
Net investment purchase and sale
-163.71%-220.69M
-512.28%-396.85M
128.53%98.27M
-227.91%-105.8M
124.46%183.69M
55.04%-83.69M
459.68%96.26M
-578.78%-344.49M
0.15%82.71M
126.07%81.84M
Cash from discontinued investing activities
Investing cash flow
-107.25%-277.78M
-714.99%-419.51M
126.80%91.34M
-292.26%-120.07M
123.98%170.46M
37.41%-134.03M
355.36%68.21M
-595.98%-340.8M
-10.16%62.45M
123.37%76.11M
Financing cash flow
Cash flow from continuing financing activities
41.37%675.84M
1,440.05%591.18M
-83.63%81.22M
-51.23%1.25M
-90.67%2.2M
-25.78%478.06M
-208.33%-44.12M
1,637.32%496.05M
-98.22%2.56M
-95.21%23.57M
Net issuance payments of debt
1,224.19%502.19M
1,227.64%502.31M
14.58%-41K
-2.56%-40K
-7.69%-42K
-151.41%-44.67M
-117,123.68%-44.55M
99.93%-48K
-100.03%-39K
0.00%-39K
Net common stock issuance
-63.15%192.6M
25,032.17%107.82M
-83.62%81.26M
-50.42%1.29M
-90.51%2.24M
957.26%522.73M
-98.95%429K
13,200.13%496.1M
8.62%2.6M
822.23%23.61M
Net other financing activities
---18.95M
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Cash from discontinued financing activities
Financing cash flow
41.37%675.84M
1,440.05%591.18M
-83.63%81.22M
-51.23%1.25M
-90.67%2.2M
-25.78%478.06M
-208.33%-44.12M
1,637.32%496.05M
-98.22%2.56M
-95.21%23.57M
Net cash flow
Beginning cash position
-39.37%242.08M
1.12%338.34M
1.13%297.3M
-24.28%264.19M
-39.37%242.08M
44.41%399.27M
-4.96%334.61M
-30.79%293.99M
12.90%348.89M
44.41%399.27M
Current changes in cash
182.52%129.48M
136.90%33.96M
2.13%41.12M
159.26%32.52M
143.54%21.88M
-228.16%-156.92M
-296.35%-92.04M
155.47%40.26M
-147.43%-54.87M
-254.87%-50.26M
Effect of exchange rate changes
357.14%702K
91.15%-43K
-123.43%-82K
2,686.96%595K
303.51%232K
-177.56%-273K
-247.27%-486K
330.26%350K
-132.86%-23K
-209.62%-114K
End cash Position
53.78%372.26M
53.78%372.26M
1.12%338.34M
1.13%297.3M
-24.28%264.19M
-39.37%242.08M
-39.37%242.08M
-4.96%334.61M
-30.79%293.99M
12.90%348.89M
Free cash flow
40.93%-325.67M
-11.22%-160.37M
-24.32%-138.37M
197.81%137.07M
-5.35%-164M
-64.32%-551.29M
-538.06%-144.18M
0.86%-111.3M
-26.90%-140.14M
-6.83%-155.67M
Currency Unit
USD
USD
USD
USD
USD
USD
USD
USD
USD
USD
Accounting Standards
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
Audit Opinions
Unqualified Opinion
--
--
--
--
Unqualified Opinion
--
--
--
--
(FY)Dec 31, 2025(Q4)Dec 31, 2025(Q3)Sep 30, 2025(Q2)Jun 30, 2025(Q1)Mar 31, 2025(FY)Dec 31, 2024(Q4)Dec 31, 2024(Q3)Sep 30, 2024(Q2)Jun 30, 2024(Q1)Mar 31, 2024
Operating Cash Flow (Indirect Method)
Cash flow from continuing operating activities 46.38%-268.58M-18.57%-137.71M-14.30%-131.44M226.24%151.34M-0.56%-150.78M-62.90%-500.95M-453.38%-116.14M-5.47%-114.99M-23.13%-119.88M-11.90%-149.94M
Net income from continuing operations 15.97%-381.39M-119.83%-229.39M8.45%-128.61M286.45%123.55M-2.90%-146.94M-23.92%-453.9M-1,026.51%-104.35M4.70%-140.48M22.31%-66.27M-14.86%-142.8M
Operating gains losses -69.55%4.06M42.84%17.14M-12,868.58%-33.85M397.70%18.86M186.86%1.91M99.79%13.33M282.62%12M-101.82%-261K132.13%3.79M-325.77%-2.2M
Depreciation and amortization 3.20%22.69M39.38%7.34M-18.04%4.5M-2.24%5.45M-4.49%5.4M-2.26%21.99M-6.15%5.27M-1.75%5.49M-1.93%5.58M0.80%5.65M
Other non cash items -21.50%27.13M1.24%5.7M-0.10%5.87M-20.22%8.14M-42.25%7.42M15.41%34.56M121.08%5.63M44.16%5.87M57.67%10.2M-23.73%12.85M
Change In working capital 75.54%-51.22M138.86%23.86M36.01%-5.41M69.71%-28.48M9.55%-41.18M-171.02%-209.39M-572.70%-61.39M-129.99%-8.46M-197.89%-94.03M17.24%-45.52M
-Change in receivables 367.42%26.13M44.18%-41.45M199.77%27.97M41.80%-12.87M-43.35%52.48M107.76%5.59M-265.93%-74.26M108.15%9.33M-59.38%-22.12M696.95%92.64M
-Change in inventory -169.65%-13.67M118.36%926K-887.82%-2.14M-1,590.72%-13.48M102.40%1.01M-105.39%-5.07M-545.58%-5.04M382.29%271K76.12%-797K398.80%499K
-Change in payables and accrued expense 245.70%36.59M-118.15%-9.45M527.03%85.82M138.72%28.9M33.29%-68.67M-218.68%-25.12M7.48%52.04M122.14%13.69M-66.70%12.11M-47.54%-102.95M
-Change in other current assets -28.44%-33.21M609.98%90.28M-8,334.34%-100.95M50.22%-10.17M-211.93%-12.37M23.42%-25.86M-14.67%-17.7M-10.58%1.23M18.31%-20.43M107.98%11.05M
-Change in other working capital 57.81%-67.05M-0.20%-16.45M51.13%-16.11M66.77%-20.86M70.86%-13.63M-1,710.46%-158.94M75.08%-16.42M-131.87%-32.97M-144.35%-62.79M-2,237.95%-46.76M
Cash from discontinued investing activities
Operating cash flow 46.38%-268.58M-18.57%-137.71M-14.30%-131.44M226.24%151.34M-0.56%-150.78M-62.90%-500.95M-453.38%-116.14M-5.47%-114.99M-23.13%-119.88M-11.90%-149.94M
Investing cash flow
Cash flow from continuing investing activities -107.25%-277.78M-714.99%-419.51M126.80%91.34M-292.26%-120.07M123.98%170.46M37.41%-134.03M355.36%68.21M-595.98%-340.8M-10.16%62.45M123.37%76.11M
Net PPE purchase and sale -13.61%-51.44M16.49%-21.29M41.81%-5.27M-97.39%-12.31M-179.92%-12.58M-90.21%-45.28M-3,213.19%-25.5M-322.98%-9.06M48.10%-6.23M57.10%-4.49M
Net intangibles purchase and sale -11.44%-5.64M46.41%-1.37M-113.02%-1.66M86.00%-1.96M47.37%-651K-20.96%-5.06M-230.78%-2.55M1,259.09%12.75M-1,222.05%-14.03M1.28%-1.24M
Net investment purchase and sale -163.71%-220.69M-512.28%-396.85M128.53%98.27M-227.91%-105.8M124.46%183.69M55.04%-83.69M459.68%96.26M-578.78%-344.49M0.15%82.71M126.07%81.84M
Cash from discontinued investing activities
Investing cash flow -107.25%-277.78M-714.99%-419.51M126.80%91.34M-292.26%-120.07M123.98%170.46M37.41%-134.03M355.36%68.21M-595.98%-340.8M-10.16%62.45M123.37%76.11M
Financing cash flow
Cash flow from continuing financing activities 41.37%675.84M1,440.05%591.18M-83.63%81.22M-51.23%1.25M-90.67%2.2M-25.78%478.06M-208.33%-44.12M1,637.32%496.05M-98.22%2.56M-95.21%23.57M
Net issuance payments of debt 1,224.19%502.19M1,227.64%502.31M14.58%-41K-2.56%-40K-7.69%-42K-151.41%-44.67M-117,123.68%-44.55M99.93%-48K-100.03%-39K0.00%-39K
Net common stock issuance -63.15%192.6M25,032.17%107.82M-83.62%81.26M-50.42%1.29M-90.51%2.24M957.26%522.73M-98.95%429K13,200.13%496.1M8.62%2.6M822.23%23.61M
Net other financing activities ---18.95M------------------------------------
Cash from discontinued financing activities
Financing cash flow 41.37%675.84M1,440.05%591.18M-83.63%81.22M-51.23%1.25M-90.67%2.2M-25.78%478.06M-208.33%-44.12M1,637.32%496.05M-98.22%2.56M-95.21%23.57M
Net cash flow
Beginning cash position -39.37%242.08M1.12%338.34M1.13%297.3M-24.28%264.19M-39.37%242.08M44.41%399.27M-4.96%334.61M-30.79%293.99M12.90%348.89M44.41%399.27M
Current changes in cash 182.52%129.48M136.90%33.96M2.13%41.12M159.26%32.52M143.54%21.88M-228.16%-156.92M-296.35%-92.04M155.47%40.26M-147.43%-54.87M-254.87%-50.26M
Effect of exchange rate changes 357.14%702K91.15%-43K-123.43%-82K2,686.96%595K303.51%232K-177.56%-273K-247.27%-486K330.26%350K-132.86%-23K-209.62%-114K
End cash Position 53.78%372.26M53.78%372.26M1.12%338.34M1.13%297.3M-24.28%264.19M-39.37%242.08M-39.37%242.08M-4.96%334.61M-30.79%293.99M12.90%348.89M
Free cash flow 40.93%-325.67M-11.22%-160.37M-24.32%-138.37M197.81%137.07M-5.35%-164M-64.32%-551.29M-538.06%-144.18M0.86%-111.3M-26.90%-140.14M-6.83%-155.67M
Currency Unit USDUSDUSDUSDUSDUSDUSDUSDUSDUSD
Accounting Standards US-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAP
Audit Opinions Unqualified Opinion--------Unqualified Opinion--------
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