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Ionis Pharmaceuticals (IONS)

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  • 75.830
  • +0.450+0.60%
Close May 12 16:00 ET
  • 75.657
  • -0.173-0.23%
Post 16:51 ET
12.53BMarket Cap-37.73P/E (TTM)

Ionis Pharmaceuticals (IONS) Cash Flow

Quarterly+Annual
YOY yoy
Hide blank lines yoy
(Q1)Mar 31, 2026
(FY)Dec 31, 2025
(Q4)Dec 31, 2025
(Q3)Sep 30, 2025
(Q2)Jun 30, 2025
(Q1)Mar 31, 2025
(FY)Dec 31, 2024
(Q4)Dec 31, 2024
(Q3)Sep 30, 2024
(Q2)Jun 30, 2024
Operating Cash Flow (Indirect Method)
Cash flow from continuing operating activities
-425.83%-792.82M
46.38%-268.58M
-18.57%-137.71M
-14.30%-131.44M
226.24%151.34M
-0.56%-150.78M
-62.90%-500.95M
-453.38%-116.14M
-5.47%-114.99M
-23.13%-119.88M
Net income from continuing operations
37.03%-92.53M
15.97%-381.39M
-119.83%-229.39M
8.45%-128.61M
286.45%123.55M
-2.90%-146.94M
-23.92%-453.9M
-1,026.51%-104.35M
4.70%-140.48M
22.31%-66.27M
Operating gains losses
-1,280.26%-22.54M
-69.55%4.06M
42.84%17.14M
-12,868.58%-33.85M
397.70%18.86M
186.86%1.91M
99.79%13.33M
282.62%12M
-101.82%-261K
132.13%3.79M
Depreciation and amortization
37.98%7.45M
3.20%22.69M
39.38%7.34M
-18.04%4.5M
-2.24%5.45M
-4.49%5.4M
-2.26%21.99M
-6.15%5.27M
-1.75%5.49M
-1.93%5.58M
Other non cash items
5.70%7.84M
-21.50%27.13M
1.24%5.7M
-0.10%5.87M
-20.22%8.14M
-42.25%7.42M
15.41%34.56M
121.08%5.63M
44.16%5.87M
57.67%10.2M
Change In working capital
-1,673.22%-730.12M
75.54%-51.22M
138.86%23.86M
36.01%-5.41M
69.71%-28.48M
9.55%-41.18M
-171.02%-209.39M
-572.70%-61.39M
-129.99%-8.46M
-197.89%-94.03M
-Change in receivables
-114.53%-7.63M
367.42%26.13M
44.18%-41.45M
199.77%27.97M
41.80%-12.87M
-43.35%52.48M
107.76%5.59M
-265.93%-74.26M
108.15%9.33M
-59.38%-22.12M
-Change in inventory
-66.53%338K
-169.65%-13.67M
118.36%926K
-887.82%-2.14M
-1,590.72%-13.48M
102.40%1.01M
-105.39%-5.07M
-545.58%-5.04M
382.29%271K
76.12%-797K
-Change in payables and accrued expense
9.31%-62.28M
245.70%36.59M
-118.15%-9.45M
527.03%85.82M
138.72%28.9M
33.29%-68.67M
-218.68%-25.12M
7.48%52.04M
122.14%13.69M
-66.70%12.11M
-Change in other current assets
40.24%-7.39M
-28.44%-33.21M
609.98%90.28M
-8,334.34%-100.95M
50.22%-10.17M
-211.93%-12.37M
23.42%-25.86M
-14.67%-17.7M
-10.58%1.23M
18.31%-20.43M
-Change in other working capital
-4,693.54%-653.17M
57.81%-67.05M
-0.20%-16.45M
51.13%-16.11M
66.77%-20.86M
70.86%-13.63M
-1,710.46%-158.94M
75.08%-16.42M
-131.87%-32.97M
-144.35%-62.79M
Cash from discontinued investing activities
Operating cash flow
-425.83%-792.82M
46.38%-268.58M
-18.57%-137.71M
-14.30%-131.44M
226.24%151.34M
-0.56%-150.78M
-62.90%-500.95M
-453.38%-116.14M
-5.47%-114.99M
-23.13%-119.88M
Investing cash flow
Cash flow from continuing investing activities
214.93%536.82M
-107.25%-277.78M
-714.99%-419.51M
126.80%91.34M
-292.26%-120.07M
123.98%170.46M
37.41%-134.03M
355.36%68.21M
-595.98%-340.8M
-10.16%62.45M
Net PPE purchase and sale
-73.04%-21.76M
-13.61%-51.44M
16.49%-21.29M
41.81%-5.27M
-97.39%-12.31M
-179.92%-12.58M
-90.21%-45.28M
-3,213.19%-25.5M
-322.98%-9.06M
48.10%-6.23M
Net intangibles purchase and sale
-128.26%-1.49M
-11.44%-5.64M
46.41%-1.37M
-113.02%-1.66M
86.00%-1.96M
47.37%-651K
-20.96%-5.06M
-230.78%-2.55M
1,259.09%12.75M
-1,222.05%-14.03M
Net investment purchase and sale
204.90%560.07M
-163.71%-220.69M
-512.28%-396.85M
128.53%98.27M
-227.91%-105.8M
124.46%183.69M
55.04%-83.69M
459.68%96.26M
-578.78%-344.49M
0.15%82.71M
Cash from discontinued investing activities
Investing cash flow
214.93%536.82M
-107.25%-277.78M
-714.99%-419.51M
126.80%91.34M
-292.26%-120.07M
123.98%170.46M
37.41%-134.03M
355.36%68.21M
-595.98%-340.8M
-10.16%62.45M
Financing cash flow
Cash flow from continuing financing activities
2,503.82%57.26M
41.37%675.84M
1,440.05%591.18M
-83.63%81.22M
-51.23%1.25M
-90.67%2.2M
-25.78%478.06M
-208.33%-44.12M
1,637.32%496.05M
-98.22%2.56M
Net issuance payments of debt
-4.76%-44K
1,224.19%502.19M
1,227.64%502.31M
14.58%-41K
-2.56%-40K
-7.69%-42K
-151.41%-44.67M
-117,123.68%-44.55M
99.93%-48K
-100.03%-39K
Net common stock issuance
2,456.98%57.3M
-63.15%192.6M
25,032.17%107.82M
-83.62%81.26M
-50.42%1.29M
-90.51%2.24M
957.26%522.73M
-98.95%429K
13,200.13%496.1M
8.62%2.6M
Net other financing activities
----
---18.95M
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----
----
----
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Cash from discontinued financing activities
Financing cash flow
2,503.82%57.26M
41.37%675.84M
1,440.05%591.18M
-83.63%81.22M
-51.23%1.25M
-90.67%2.2M
-25.78%478.06M
-208.33%-44.12M
1,637.32%496.05M
-98.22%2.56M
Net cash flow
Beginning cash position
53.78%372.26M
-39.37%242.08M
1.12%338.34M
1.13%297.3M
-24.28%264.19M
-39.37%242.08M
44.41%399.27M
-4.96%334.61M
-30.79%293.99M
12.90%348.89M
Current changes in cash
-1,008.20%-198.74M
182.52%129.48M
136.90%33.96M
2.13%41.12M
159.26%32.52M
143.54%21.88M
-228.16%-156.92M
-296.35%-92.04M
155.47%40.26M
-147.43%-54.87M
Effect of exchange rate changes
-159.48%-138K
357.14%702K
91.15%-43K
-123.43%-82K
2,686.96%595K
303.51%232K
-177.56%-273K
-247.27%-486K
330.26%350K
-132.86%-23K
End cash Position
-34.37%173.38M
53.78%372.26M
53.78%372.26M
1.12%338.34M
1.13%297.3M
-24.28%264.19M
-39.37%242.08M
-39.37%242.08M
-4.96%334.61M
-30.79%293.99M
Free cash flow
-397.59%-816.07M
40.93%-325.67M
-11.22%-160.37M
-24.32%-138.37M
197.81%137.07M
-5.35%-164M
-64.32%-551.29M
-538.06%-144.18M
0.86%-111.3M
-26.90%-140.14M
Currency Unit
USD
USD
USD
USD
USD
USD
USD
USD
USD
USD
Accounting Standards
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
Audit Opinions
--
Unqualified Opinion
--
--
--
--
Unqualified Opinion
--
--
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(Q1)Mar 31, 2026(FY)Dec 31, 2025(Q4)Dec 31, 2025(Q3)Sep 30, 2025(Q2)Jun 30, 2025(Q1)Mar 31, 2025(FY)Dec 31, 2024(Q4)Dec 31, 2024(Q3)Sep 30, 2024(Q2)Jun 30, 2024
Operating Cash Flow (Indirect Method)
Cash flow from continuing operating activities -425.83%-792.82M46.38%-268.58M-18.57%-137.71M-14.30%-131.44M226.24%151.34M-0.56%-150.78M-62.90%-500.95M-453.38%-116.14M-5.47%-114.99M-23.13%-119.88M
Net income from continuing operations 37.03%-92.53M15.97%-381.39M-119.83%-229.39M8.45%-128.61M286.45%123.55M-2.90%-146.94M-23.92%-453.9M-1,026.51%-104.35M4.70%-140.48M22.31%-66.27M
Operating gains losses -1,280.26%-22.54M-69.55%4.06M42.84%17.14M-12,868.58%-33.85M397.70%18.86M186.86%1.91M99.79%13.33M282.62%12M-101.82%-261K132.13%3.79M
Depreciation and amortization 37.98%7.45M3.20%22.69M39.38%7.34M-18.04%4.5M-2.24%5.45M-4.49%5.4M-2.26%21.99M-6.15%5.27M-1.75%5.49M-1.93%5.58M
Other non cash items 5.70%7.84M-21.50%27.13M1.24%5.7M-0.10%5.87M-20.22%8.14M-42.25%7.42M15.41%34.56M121.08%5.63M44.16%5.87M57.67%10.2M
Change In working capital -1,673.22%-730.12M75.54%-51.22M138.86%23.86M36.01%-5.41M69.71%-28.48M9.55%-41.18M-171.02%-209.39M-572.70%-61.39M-129.99%-8.46M-197.89%-94.03M
-Change in receivables -114.53%-7.63M367.42%26.13M44.18%-41.45M199.77%27.97M41.80%-12.87M-43.35%52.48M107.76%5.59M-265.93%-74.26M108.15%9.33M-59.38%-22.12M
-Change in inventory -66.53%338K-169.65%-13.67M118.36%926K-887.82%-2.14M-1,590.72%-13.48M102.40%1.01M-105.39%-5.07M-545.58%-5.04M382.29%271K76.12%-797K
-Change in payables and accrued expense 9.31%-62.28M245.70%36.59M-118.15%-9.45M527.03%85.82M138.72%28.9M33.29%-68.67M-218.68%-25.12M7.48%52.04M122.14%13.69M-66.70%12.11M
-Change in other current assets 40.24%-7.39M-28.44%-33.21M609.98%90.28M-8,334.34%-100.95M50.22%-10.17M-211.93%-12.37M23.42%-25.86M-14.67%-17.7M-10.58%1.23M18.31%-20.43M
-Change in other working capital -4,693.54%-653.17M57.81%-67.05M-0.20%-16.45M51.13%-16.11M66.77%-20.86M70.86%-13.63M-1,710.46%-158.94M75.08%-16.42M-131.87%-32.97M-144.35%-62.79M
Cash from discontinued investing activities
Operating cash flow -425.83%-792.82M46.38%-268.58M-18.57%-137.71M-14.30%-131.44M226.24%151.34M-0.56%-150.78M-62.90%-500.95M-453.38%-116.14M-5.47%-114.99M-23.13%-119.88M
Investing cash flow
Cash flow from continuing investing activities 214.93%536.82M-107.25%-277.78M-714.99%-419.51M126.80%91.34M-292.26%-120.07M123.98%170.46M37.41%-134.03M355.36%68.21M-595.98%-340.8M-10.16%62.45M
Net PPE purchase and sale -73.04%-21.76M-13.61%-51.44M16.49%-21.29M41.81%-5.27M-97.39%-12.31M-179.92%-12.58M-90.21%-45.28M-3,213.19%-25.5M-322.98%-9.06M48.10%-6.23M
Net intangibles purchase and sale -128.26%-1.49M-11.44%-5.64M46.41%-1.37M-113.02%-1.66M86.00%-1.96M47.37%-651K-20.96%-5.06M-230.78%-2.55M1,259.09%12.75M-1,222.05%-14.03M
Net investment purchase and sale 204.90%560.07M-163.71%-220.69M-512.28%-396.85M128.53%98.27M-227.91%-105.8M124.46%183.69M55.04%-83.69M459.68%96.26M-578.78%-344.49M0.15%82.71M
Cash from discontinued investing activities
Investing cash flow 214.93%536.82M-107.25%-277.78M-714.99%-419.51M126.80%91.34M-292.26%-120.07M123.98%170.46M37.41%-134.03M355.36%68.21M-595.98%-340.8M-10.16%62.45M
Financing cash flow
Cash flow from continuing financing activities 2,503.82%57.26M41.37%675.84M1,440.05%591.18M-83.63%81.22M-51.23%1.25M-90.67%2.2M-25.78%478.06M-208.33%-44.12M1,637.32%496.05M-98.22%2.56M
Net issuance payments of debt -4.76%-44K1,224.19%502.19M1,227.64%502.31M14.58%-41K-2.56%-40K-7.69%-42K-151.41%-44.67M-117,123.68%-44.55M99.93%-48K-100.03%-39K
Net common stock issuance 2,456.98%57.3M-63.15%192.6M25,032.17%107.82M-83.62%81.26M-50.42%1.29M-90.51%2.24M957.26%522.73M-98.95%429K13,200.13%496.1M8.62%2.6M
Net other financing activities -------18.95M--------------------------------
Cash from discontinued financing activities
Financing cash flow 2,503.82%57.26M41.37%675.84M1,440.05%591.18M-83.63%81.22M-51.23%1.25M-90.67%2.2M-25.78%478.06M-208.33%-44.12M1,637.32%496.05M-98.22%2.56M
Net cash flow
Beginning cash position 53.78%372.26M-39.37%242.08M1.12%338.34M1.13%297.3M-24.28%264.19M-39.37%242.08M44.41%399.27M-4.96%334.61M-30.79%293.99M12.90%348.89M
Current changes in cash -1,008.20%-198.74M182.52%129.48M136.90%33.96M2.13%41.12M159.26%32.52M143.54%21.88M-228.16%-156.92M-296.35%-92.04M155.47%40.26M-147.43%-54.87M
Effect of exchange rate changes -159.48%-138K357.14%702K91.15%-43K-123.43%-82K2,686.96%595K303.51%232K-177.56%-273K-247.27%-486K330.26%350K-132.86%-23K
End cash Position -34.37%173.38M53.78%372.26M53.78%372.26M1.12%338.34M1.13%297.3M-24.28%264.19M-39.37%242.08M-39.37%242.08M-4.96%334.61M-30.79%293.99M
Free cash flow -397.59%-816.07M40.93%-325.67M-11.22%-160.37M-24.32%-138.37M197.81%137.07M-5.35%-164M-64.32%-551.29M-538.06%-144.18M0.86%-111.3M-26.90%-140.14M
Currency Unit USDUSDUSDUSDUSDUSDUSDUSDUSDUSD
Accounting Standards US-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAP
Audit Opinions --Unqualified Opinion--------Unqualified Opinion------
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