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Karyopharm Therapeutics (KPTI)

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8.660
-0.090-1.03%

Close Apr 24 15:59 ET

8.660
0.0000.00%

Post 16:10 ET

195.23MMarket Cap-0.48P/E (TTM)

Earnings

Revenue Breakdown

Financial Indicators

Income Statement

Balance Sheet

Cash Flow

Karyopharm Therapeutics (KPTI) Balance Sheet

Quarterly+Annual

YOY

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(FY)Dec 31, 2025

(Q4)Dec 31, 2025

(Q3)Sep 30, 2025

(Q2)Jun 30, 2025

(Q1)Mar 31, 2025

(FY)Dec 31, 2024

(Q4)Dec 31, 2024

(Q3)Sep 30, 2024

(Q2)Jun 30, 2024

(Q1)Mar 31, 2024

Assets

Current assets

Cash, cash equivalents and short term investments

-41.36%63.74M

-65.64%45.88M

-66.02%51.7M

-52.93%69.94M

-43.21%108.71M

-35.90%133.53M

-35.75%152.12M

-42.94%148.58M

-Cash and cash equivalents

-3.10%60.54M

-48.27%37.67M

-54.32%38.73M

26.63%38.78M

19.61%62.48M

66.83%72.83M

4.80%84.77M

-63.56%30.63M

-Short-term investments

-93.07%3.2M

-86.48%8.21M

-80.74%12.97M

-73.58%31.16M

-66.79%46.24M

-63.14%60.7M

-56.79%67.35M

-33.11%117.95M

Receivables

-14.91%26.18M

0.31%31.88M

-13.33%32.93M

13.39%35.24M

14.11%30.77M

-16.20%31.78M

17.70%38M

-11.70%31.08M

-Accounts receivable

-14.91%26.18M

0.31%31.88M

-13.33%32.93M

13.39%35.24M

14.11%30.77M

-16.20%31.78M

17.70%38M

-11.70%31.08M

Inventory

-14.79%4.04M

-15.11%3.97M

43.61%4.99M

72.23%4.77M

55.73%4.74M

50.47%4.67M

-5.34%3.48M

-27.65%2.77M

Restricted cash

----

-95.45%30K

-93.94%33K

-94.36%32K

-45.74%459K

Other current assets

-24.98%9.19M

-45.57%8.03M

-44.69%8.25M

-33.55%10.29M

3.66%12.25M

10.59%14.75M

-17.59%14.91M

-15.35%15.48M

Total current assets

-34.08%103.15M

-51.42%89.75M

-53.07%97.87M

-39.39%120.24M

-33.11%156.46M

-29.81%184.76M

-28.43%208.54M

-37.73%198.37M

Non current assets

Net PPE

-25.97%4.65M

55.86%4.8M

40.17%5.33M

30.20%5.8M

28.72%6.28M

-43.80%3.08M

-37.33%3.8M

-32.77%4.45M

-Gross PPE

-21.68%10.16M

55.86%4.8M

40.17%5.33M

30.20%5.8M

13.35%12.98M

-43.80%3.08M

-37.33%3.8M

-32.77%4.45M

-Accumulated depreciation

17.65%-5.51M

----

-1.92%-6.69M

----

Other non current assets

-63.04%618K

2.68%1.68M

2.81%1.68M

2.20%1.67M

2.26%1.67M

30.57%1.64M

323.26%1.64M

158.36%1.64M

Total non current assets

-33.76%5.27M

37.39%6.49M

28.91%7.01M

22.67%7.47M

22.08%7.96M

-29.93%4.72M

-15.69%5.44M

-16.08%6.09M

Total assets

-34.06%108.42M

-49.21%96.23M

-50.99%104.88M

-37.54%127.71M

-31.62%164.42M

-29.81%189.48M

-28.15%213.98M

-37.24%204.46M

Liabilities

Current liabilities

Payables

-21.62%4M

-6.76%5.39M

-7.15%2.6M

16.79%5.87M

63.53%5.11M

513.26%5.78M

22.30%2.8M

-44.41%5.03M

-accounts payable

-21.62%4M

-6.76%5.39M

-7.15%2.6M

16.79%5.87M

63.53%5.11M

513.26%5.78M

22.30%2.8M

-44.41%5.03M

Current accrued expenses

28.63%60.12M

32.38%66.33M

26.34%62.93M

4.23%57.17M

4.13%46.74M

-10.07%50.11M

-3.86%49.81M

16.62%54.85M

Current debt and capital lease obligation

-11.60%21.98M

272.74%13.67M

805.98%32.12M

641.20%25.39M

651.63%24.86M

14.80%3.67M

14.95%3.55M

15.05%3.43M

-Current debt

-13.99%21.01M

--12.75M

--30.73M

--24.46M

--24.43M

----

-Current capital lease obligation

121.23%969K

-74.86%922K

-60.99%1.38M

-72.93%927K

-86.76%438K

14.80%3.67M

14.95%3.55M

15.05%3.43M

Other current liabilities

-3.72%1.58M

-8.88%1.77M

7.15%1.57M

-4.76%1.94M

-0.79%1.64M

-13.06%1.94M

-16.07%1.47M

-18.55%2.04M

Current liabilities

-0.22%92.06M

41.73%87.16M

72.19%99.22M

38.31%90.37M

32.79%92.26M

-0.94%61.49M

-2.22%57.62M

6.15%65.34M

Non current liabilities

Long term debt and capital lease obligation

24.74%211.63M

-4.11%182.75M

-17.48%158.5M

-6.76%161.32M

-2.33%169.66M

9.30%190.59M

9.77%192.09M

-1.48%173.01M

-Long term debt

26.35%205.89M

-7.27%176.74M

-20.34%152.25M

-9.52%154.83M

-4.66%162.95M

11.65%190.59M

12.10%191.13M

0.48%171.13M

-Long term capital lease obligation

-14.44%5.74M

--6.01M

554.55%6.25M

244.21%6.49M

140.66%6.71M

--0

-78.78%955K

-64.52%1.88M

Non current deferred liabilities

-1.58%72.34M

0.00%73.5M

-44.52%73.5M

-44.62%73.5M

-0.18%132.48M

Derivative product liabilities

13.03%14.22M

-54.11%7.97M

-76.74%4.33M

--3.26M

--12.58M

--17.36M

--18.63M

----

Other non current liabilities

356.58%11.1M

128.30%14.12M

92.85%8.26M

99.30%5.15M

148.47%2.43M

333.05%6.18M

75.81%4.28M

137.97%2.58M

Total non current liabilities

19.80%309.28M

-3.23%278.33M

-15.22%244.59M

-21.05%243.23M

-15.95%258.17M

-6.70%287.63M

-6.98%288.5M

-0.44%308.07M

Total liabilities

14.53%401.34M

4.69%365.49M

-0.67%343.81M

-10.66%333.6M

-6.96%350.44M

-5.73%349.12M

-6.22%346.12M

0.66%373.41M

Shareholders'equity

Share capital

7.69%14K

0.00%13K

8.33%13K

0.00%12K

-common stock

7.69%14K

0.00%13K

8.33%13K

0.00%12K

-Preferred stock

--0

Retained earnings

-12.54%-1.76B

-8.13%-1.66B

-8.23%-1.62B

-4.10%-1.59B

-5.14%-1.56B

-6.05%-1.53B

-6.37%-1.5B

-10.62%-1.52B

Paid-in capital

6.44%1.47B

1.10%1.39B

1.20%1.39B

1.87%1.38B

1.98%1.38B

2.06%1.37B

2.15%1.37B

1.70%1.36B

Gains losses not affecting retained earnings

119.94%71K

-16.67%-259K

58.51%-251K

38.03%-321K

-121.12%-356K

70.08%-222K

22.73%-605K

-23.63%-518K

Total stockholders'equity

-57.47%-292.93M

-68.66%-269.26M

-80.81%-238.93M

-21.86%-205.88M

-36.57%-186.02M

-59.02%-159.65M

-85.46%-132.14M

-274.01%-168.96M

Total equity

-57.47%-292.93M

-68.66%-269.26M

-80.81%-238.93M

-21.86%-205.88M

-36.57%-186.02M

-59.02%-159.65M

-85.46%-132.14M

-274.01%-168.96M

Currency Unit

USD

Accounting Standards

US-GAAP

Audit Opinions

Unqualified Opinion with Explanatory Notes

Unqualified Opinion

	(FY)Dec 31, 2025	(Q4)Dec 31, 2025	(Q3)Sep 30, 2025	(Q2)Jun 30, 2025	(Q1)Mar 31, 2025	(FY)Dec 31, 2024	(Q4)Dec 31, 2024	(Q3)Sep 30, 2024	(Q2)Jun 30, 2024	(Q1)Mar 31, 2024
Assets
Current assets
Cash, cash equivalents and short term investments	-41.36%63.74M	-41.36%63.74M	-65.64%45.88M	-66.02%51.7M	-52.93%69.94M	-43.21%108.71M	-43.21%108.71M	-35.90%133.53M	-35.75%152.12M	-42.94%148.58M
-Cash and cash equivalents	-3.10%60.54M	-3.10%60.54M	-48.27%37.67M	-54.32%38.73M	26.63%38.78M	19.61%62.48M	19.61%62.48M	66.83%72.83M	4.80%84.77M	-63.56%30.63M
-Short-term investments	-93.07%3.2M	-93.07%3.2M	-86.48%8.21M	-80.74%12.97M	-73.58%31.16M	-66.79%46.24M	-66.79%46.24M	-63.14%60.7M	-56.79%67.35M	-33.11%117.95M
Receivables	-14.91%26.18M	-14.91%26.18M	0.31%31.88M	-13.33%32.93M	13.39%35.24M	14.11%30.77M	14.11%30.77M	-16.20%31.78M	17.70%38M	-11.70%31.08M
-Accounts receivable	-14.91%26.18M	-14.91%26.18M	0.31%31.88M	-13.33%32.93M	13.39%35.24M	14.11%30.77M	14.11%30.77M	-16.20%31.78M	17.70%38M	-11.70%31.08M
Inventory	-14.79%4.04M	-14.79%4.04M	-15.11%3.97M	43.61%4.99M	72.23%4.77M	55.73%4.74M	55.73%4.74M	50.47%4.67M	-5.34%3.48M	-27.65%2.77M
Restricted cash	----	----	----	----	----	-95.45%30K	-95.45%30K	-93.94%33K	-94.36%32K	-45.74%459K
Other current assets	-24.98%9.19M	-24.98%9.19M	-45.57%8.03M	-44.69%8.25M	-33.55%10.29M	3.66%12.25M	3.66%12.25M	10.59%14.75M	-17.59%14.91M	-15.35%15.48M
Total current assets	-34.08%103.15M	-34.08%103.15M	-51.42%89.75M	-53.07%97.87M	-39.39%120.24M	-33.11%156.46M	-33.11%156.46M	-29.81%184.76M	-28.43%208.54M	-37.73%198.37M
Non current assets
Net PPE	-25.97%4.65M	-25.97%4.65M	55.86%4.8M	40.17%5.33M	30.20%5.8M	28.72%6.28M	28.72%6.28M	-43.80%3.08M	-37.33%3.8M	-32.77%4.45M
-Gross PPE	-21.68%10.16M	-21.68%10.16M	55.86%4.8M	40.17%5.33M	30.20%5.8M	13.35%12.98M	13.35%12.98M	-43.80%3.08M	-37.33%3.8M	-32.77%4.45M
-Accumulated depreciation	17.65%-5.51M	17.65%-5.51M	----	----	----	-1.92%-6.69M	-1.92%-6.69M	----	----	----
Other non current assets	-63.04%618K	-63.04%618K	2.68%1.68M	2.81%1.68M	2.20%1.67M	2.26%1.67M	2.26%1.67M	30.57%1.64M	323.26%1.64M	158.36%1.64M
Total non current assets	-33.76%5.27M	-33.76%5.27M	37.39%6.49M	28.91%7.01M	22.67%7.47M	22.08%7.96M	22.08%7.96M	-29.93%4.72M	-15.69%5.44M	-16.08%6.09M
Total assets	-34.06%108.42M	-34.06%108.42M	-49.21%96.23M	-50.99%104.88M	-37.54%127.71M	-31.62%164.42M	-31.62%164.42M	-29.81%189.48M	-28.15%213.98M	-37.24%204.46M
Liabilities
Current liabilities
Payables	-21.62%4M	-21.62%4M	-6.76%5.39M	-7.15%2.6M	16.79%5.87M	63.53%5.11M	63.53%5.11M	513.26%5.78M	22.30%2.8M	-44.41%5.03M
-accounts payable	-21.62%4M	-21.62%4M	-6.76%5.39M	-7.15%2.6M	16.79%5.87M	63.53%5.11M	63.53%5.11M	513.26%5.78M	22.30%2.8M	-44.41%5.03M
Current accrued expenses	28.63%60.12M	28.63%60.12M	32.38%66.33M	26.34%62.93M	4.23%57.17M	4.13%46.74M	4.13%46.74M	-10.07%50.11M	-3.86%49.81M	16.62%54.85M
Current debt and capital lease obligation	-11.60%21.98M	-11.60%21.98M	272.74%13.67M	805.98%32.12M	641.20%25.39M	651.63%24.86M	651.63%24.86M	14.80%3.67M	14.95%3.55M	15.05%3.43M
-Current debt	-13.99%21.01M	-13.99%21.01M	--12.75M	--30.73M	--24.46M	--24.43M	--24.43M	----	----	----
-Current capital lease obligation	121.23%969K	121.23%969K	-74.86%922K	-60.99%1.38M	-72.93%927K	-86.76%438K	-86.76%438K	14.80%3.67M	14.95%3.55M	15.05%3.43M
Other current liabilities	-3.72%1.58M	-3.72%1.58M	-8.88%1.77M	7.15%1.57M	-4.76%1.94M	-0.79%1.64M	-0.79%1.64M	-13.06%1.94M	-16.07%1.47M	-18.55%2.04M
Current liabilities	-0.22%92.06M	-0.22%92.06M	41.73%87.16M	72.19%99.22M	38.31%90.37M	32.79%92.26M	32.79%92.26M	-0.94%61.49M	-2.22%57.62M	6.15%65.34M
Non current liabilities
Long term debt and capital lease obligation	24.74%211.63M	24.74%211.63M	-4.11%182.75M	-17.48%158.5M	-6.76%161.32M	-2.33%169.66M	-2.33%169.66M	9.30%190.59M	9.77%192.09M	-1.48%173.01M
-Long term debt	26.35%205.89M	26.35%205.89M	-7.27%176.74M	-20.34%152.25M	-9.52%154.83M	-4.66%162.95M	-4.66%162.95M	11.65%190.59M	12.10%191.13M	0.48%171.13M
-Long term capital lease obligation	-14.44%5.74M	-14.44%5.74M	--6.01M	554.55%6.25M	244.21%6.49M	140.66%6.71M	140.66%6.71M	--0	-78.78%955K	-64.52%1.88M
Non current deferred liabilities	-1.58%72.34M	-1.58%72.34M	0.00%73.5M	0.00%73.5M	-44.52%73.5M	-44.52%73.5M	-44.52%73.5M	-44.52%73.5M	-44.62%73.5M	-0.18%132.48M
Derivative product liabilities	13.03%14.22M	13.03%14.22M	-54.11%7.97M	-76.74%4.33M	--3.26M	--12.58M	--12.58M	--17.36M	--18.63M	----
Other non current liabilities	356.58%11.1M	356.58%11.1M	128.30%14.12M	92.85%8.26M	99.30%5.15M	148.47%2.43M	148.47%2.43M	333.05%6.18M	75.81%4.28M	137.97%2.58M
Total non current liabilities	19.80%309.28M	19.80%309.28M	-3.23%278.33M	-15.22%244.59M	-21.05%243.23M	-15.95%258.17M	-15.95%258.17M	-6.70%287.63M	-6.98%288.5M	-0.44%308.07M
Total liabilities	14.53%401.34M	14.53%401.34M	4.69%365.49M	-0.67%343.81M	-10.66%333.6M	-6.96%350.44M	-6.96%350.44M	-5.73%349.12M	-6.22%346.12M	0.66%373.41M
Shareholders'equity
Share capital	7.69%14K	7.69%14K	0.00%13K	0.00%13K	8.33%13K	8.33%13K	8.33%13K	8.33%13K	8.33%13K	0.00%12K
-common stock	7.69%14K	7.69%14K	0.00%13K	0.00%13K	8.33%13K	8.33%13K	8.33%13K	8.33%13K	8.33%13K	0.00%12K
-Preferred stock	--0	--0	--0	--0	--0	--0	--0	--0	--0	--0
Retained earnings	-12.54%-1.76B	-12.54%-1.76B	-8.13%-1.66B	-8.23%-1.62B	-4.10%-1.59B	-5.14%-1.56B	-5.14%-1.56B	-6.05%-1.53B	-6.37%-1.5B	-10.62%-1.52B
Paid-in capital	6.44%1.47B	6.44%1.47B	1.10%1.39B	1.20%1.39B	1.87%1.38B	1.98%1.38B	1.98%1.38B	2.06%1.37B	2.15%1.37B	1.70%1.36B
Gains losses not affecting retained earnings	119.94%71K	119.94%71K	-16.67%-259K	58.51%-251K	38.03%-321K	-121.12%-356K	-121.12%-356K	70.08%-222K	22.73%-605K	-23.63%-518K
Total stockholders'equity	-57.47%-292.93M	-57.47%-292.93M	-68.66%-269.26M	-80.81%-238.93M	-21.86%-205.88M	-36.57%-186.02M	-36.57%-186.02M	-59.02%-159.65M	-85.46%-132.14M	-274.01%-168.96M
Total equity	-57.47%-292.93M	-57.47%-292.93M	-68.66%-269.26M	-80.81%-238.93M	-21.86%-205.88M	-36.57%-186.02M	-36.57%-186.02M	-59.02%-159.65M	-85.46%-132.14M	-274.01%-168.96M
Currency Unit	USD	USD	USD	USD	USD	USD	USD	USD	USD	USD
Accounting Standards	US-GAAP	US-GAAP	US-GAAP	US-GAAP	US-GAAP	US-GAAP	US-GAAP	US-GAAP	US-GAAP	US-GAAP
Audit Opinions	Unqualified Opinion with Explanatory Notes	--	--	--	--	Unqualified Opinion	--	--	--	--

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