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UpStream Bio (UPB)

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  • 9.300
  • -0.300-3.13%
Close Apr 24 16:00 ET
  • 9.300
  • 0.0000.00%
Post 16:17 ET
506.11MMarket Cap-3.50P/E (TTM)

Earnings

Revenue Breakdown

Financial Indicators

Income Statement

Balance Sheet

Cash Flow

UpStream Bio (UPB) Cash Flow

Quarterly+Annual
YOY yoy
Hide blank lines yoy
(FY)Dec 31, 2025
(Q4)Dec 31, 2025
(Q3)Sep 30, 2025
(Q2)Jun 30, 2025
(Q1)Mar 31, 2025
(FY)Dec 31, 2024
(Q4)Dec 31, 2024
(Q3)Sep 30, 2024
(Q2)Jun 30, 2024
(Q1)Mar 31, 2024
Operating Cash Flow (Indirect Method)
Cash flow from continuing operating activities
-125.23%-133.28M
-56.18%-30.63M
-59.29%-22.24M
-388.29%-39.24M
-134.40%-41.17M
-56.02%-59.17M
-21.74%-19.61M
-189.73%-13.96M
-8.04M
-17.56M
Net income from continuing operations
-128.39%-143.44M
-99.88%-42.46M
-111.03%-33.75M
-172.29%-39.97M
-150.32%-27.27M
-205.82%-62.81M
-79.51%-21.24M
-415.54%-15.99M
---14.68M
---10.89M
Depreciation and amortization
111.24%188K
16.33%57K
228.57%46K
223.08%42K
230.77%43K
48.33%89K
250.00%49K
-17.65%14K
--13K
--13K
Other non cash items
120.96%561K
11.45%146K
1,687.50%143K
527.27%138K
104.72%134K
82.52%-2.68M
115.82%131K
100.17%8K
--22K
---2.84M
Change In working capital
-68.55%589K
687.78%7.75M
1,138.35%8.88M
-116.81%-1.07M
-287.57%-14.97M
143.51%1.87M
67.28%-1.32M
-76.55%717K
--6.34M
---3.86M
-Change in receivables
89.32%-55K
350.00%15K
361.86%254K
-262.72%-371K
107.34%47K
-264.01%-515K
-103.59%-6K
44.89%-97K
--228K
---640K
-Change in prepaid assets
-51.19%-1.52M
400.96%6.29M
1,005.21%7.85M
-192.28%-1.91M
-707.58%-13.75M
83.84%-1.01M
64.92%-2.09M
-75.86%710K
--2.07M
---1.7M
-Change in payables and accrued expense
-22.56%2.73M
80.43%1.6M
982.35%920K
-66.54%1.36M
23.95%-1.14M
107.59%3.53M
-63.11%884K
-89.27%85K
--4.06M
---1.5M
-Change in other current liabilities
-324.81%-565K
-40.19%-150K
-847.37%-142K
-504.35%-139K
-509.09%-134K
-62.20%-133K
-435.00%-107K
135.19%19K
---23K
---22K
Cash from discontinued investing activities
Operating cash flow
-125.23%-133.28M
-56.18%-30.63M
-59.29%-22.24M
-388.29%-39.24M
-134.40%-41.17M
-56.02%-59.17M
-21.74%-19.61M
-189.73%-13.96M
---8.04M
---17.56M
Investing cash flow
Cash flow from continuing investing activities
-57.15%-93.48M
40.65%58.94M
3,319.87%48.19M
110.95%12.77M
-1,640.43%-213.38M
28.19%-59.49M
899.47%41.91M
-88.50%1.41M
-116.65M
13.85M
Net PPE purchase and sale
67.71%-165K
70.81%-54K
80.37%-64K
----
----
-254.86%-511K
---185K
---326K
----
----
Net investment purchase and sale
-58.23%-93.32M
40.16%59M
2,680.98%48.25M
110.99%12.82M
-1,640.43%-213.38M
28.69%-58.97M
903.00%42.09M
-85.84%1.74M
---116.65M
--13.85M
Cash from discontinued investing activities
Investing cash flow
-57.15%-93.48M
40.65%58.94M
3,319.87%48.19M
110.95%12.77M
-1,640.43%-213.38M
28.19%-59.49M
899.47%41.91M
-88.50%1.41M
---116.65M
--13.85M
Financing cash flow
Cash flow from continuing financing activities
-99.42%2.44M
-99.59%1.1M
146.31%760K
-99.56%612K
-100.36%-34K
223.36%418.91M
203,594.74%270.65M
-3,382.00%-1.64M
140.52M
9.39M
Net common stock issuance
--0
----
----
----
----
--272.72M
----
----
----
----
Net preferred stock issuance
--0
--0
--0
----
----
15.83%149.92M
--0
--0
----
----
Proceeds from stock option exercised by employees
1,456.60%2.48M
3,839.29%1.1M
3,900.00%760K
512.00%612K
--0
34.75%159K
--28K
-81.00%19K
--100K
--12K
Net other financing activities
99.13%-34K
--0
--0
--0
-100.36%-34K
---3.9M
---2.1M
---1.66M
---9.51M
--9.38M
Cash from discontinued financing activities
Financing cash flow
-99.42%2.44M
-99.59%1.1M
146.31%760K
-99.56%612K
-100.36%-34K
223.36%418.91M
203,594.74%270.65M
-3,382.00%-1.64M
--140.52M
--9.39M
Net cash flow
Beginning cash position
1,162.28%326.09M
118.33%72.36M
-3.56%45.65M
126.93%71.51M
1,162.28%326.09M
51.50%25.83M
-29.96%33.14M
18.82%47.34M
--31.51M
--25.83M
Current changes in cash
-174.71%-224.31M
-89.96%29.41M
288.15%26.71M
-263.36%-25.85M
-4,584.41%-254.58M
3,318.96%300.25M
1,463.48%292.94M
-289.76%-14.19M
--15.83M
--5.68M
End cash Position
-68.79%101.77M
-68.79%101.77M
118.33%72.36M
-3.56%45.65M
126.93%71.51M
1,162.28%326.09M
1,162.28%326.09M
-29.96%33.14M
--47.34M
--31.51M
Free cash flow
-123.58%-133.44M
-55.00%-30.69M
-56.10%-22.3M
-388.88%-39.29M
-134.40%-41.17M
-56.77%-59.68M
-22.89%-19.8M
-196.49%-14.29M
---8.04M
---17.56M
Currency Unit
USD
USD
USD
USD
USD
USD
USD
USD
USD
USD
Accounting Standards
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
US-GAAP
Audit Opinions
Unqualified Opinion
--
--
--
--
Unqualified Opinion
--
--
--
--
(FY)Dec 31, 2025(Q4)Dec 31, 2025(Q3)Sep 30, 2025(Q2)Jun 30, 2025(Q1)Mar 31, 2025(FY)Dec 31, 2024(Q4)Dec 31, 2024(Q3)Sep 30, 2024(Q2)Jun 30, 2024(Q1)Mar 31, 2024
Operating Cash Flow (Indirect Method)
Cash flow from continuing operating activities -125.23%-133.28M-56.18%-30.63M-59.29%-22.24M-388.29%-39.24M-134.40%-41.17M-56.02%-59.17M-21.74%-19.61M-189.73%-13.96M-8.04M-17.56M
Net income from continuing operations -128.39%-143.44M-99.88%-42.46M-111.03%-33.75M-172.29%-39.97M-150.32%-27.27M-205.82%-62.81M-79.51%-21.24M-415.54%-15.99M---14.68M---10.89M
Depreciation and amortization 111.24%188K16.33%57K228.57%46K223.08%42K230.77%43K48.33%89K250.00%49K-17.65%14K--13K--13K
Other non cash items 120.96%561K11.45%146K1,687.50%143K527.27%138K104.72%134K82.52%-2.68M115.82%131K100.17%8K--22K---2.84M
Change In working capital -68.55%589K687.78%7.75M1,138.35%8.88M-116.81%-1.07M-287.57%-14.97M143.51%1.87M67.28%-1.32M-76.55%717K--6.34M---3.86M
-Change in receivables 89.32%-55K350.00%15K361.86%254K-262.72%-371K107.34%47K-264.01%-515K-103.59%-6K44.89%-97K--228K---640K
-Change in prepaid assets -51.19%-1.52M400.96%6.29M1,005.21%7.85M-192.28%-1.91M-707.58%-13.75M83.84%-1.01M64.92%-2.09M-75.86%710K--2.07M---1.7M
-Change in payables and accrued expense -22.56%2.73M80.43%1.6M982.35%920K-66.54%1.36M23.95%-1.14M107.59%3.53M-63.11%884K-89.27%85K--4.06M---1.5M
-Change in other current liabilities -324.81%-565K-40.19%-150K-847.37%-142K-504.35%-139K-509.09%-134K-62.20%-133K-435.00%-107K135.19%19K---23K---22K
Cash from discontinued investing activities
Operating cash flow -125.23%-133.28M-56.18%-30.63M-59.29%-22.24M-388.29%-39.24M-134.40%-41.17M-56.02%-59.17M-21.74%-19.61M-189.73%-13.96M---8.04M---17.56M
Investing cash flow
Cash flow from continuing investing activities -57.15%-93.48M40.65%58.94M3,319.87%48.19M110.95%12.77M-1,640.43%-213.38M28.19%-59.49M899.47%41.91M-88.50%1.41M-116.65M13.85M
Net PPE purchase and sale 67.71%-165K70.81%-54K80.37%-64K---------254.86%-511K---185K---326K--------
Net investment purchase and sale -58.23%-93.32M40.16%59M2,680.98%48.25M110.99%12.82M-1,640.43%-213.38M28.69%-58.97M903.00%42.09M-85.84%1.74M---116.65M--13.85M
Cash from discontinued investing activities
Investing cash flow -57.15%-93.48M40.65%58.94M3,319.87%48.19M110.95%12.77M-1,640.43%-213.38M28.19%-59.49M899.47%41.91M-88.50%1.41M---116.65M--13.85M
Financing cash flow
Cash flow from continuing financing activities -99.42%2.44M-99.59%1.1M146.31%760K-99.56%612K-100.36%-34K223.36%418.91M203,594.74%270.65M-3,382.00%-1.64M140.52M9.39M
Net common stock issuance --0------------------272.72M----------------
Net preferred stock issuance --0--0--0--------15.83%149.92M--0--0--------
Proceeds from stock option exercised by employees 1,456.60%2.48M3,839.29%1.1M3,900.00%760K512.00%612K--034.75%159K--28K-81.00%19K--100K--12K
Net other financing activities 99.13%-34K--0--0--0-100.36%-34K---3.9M---2.1M---1.66M---9.51M--9.38M
Cash from discontinued financing activities
Financing cash flow -99.42%2.44M-99.59%1.1M146.31%760K-99.56%612K-100.36%-34K223.36%418.91M203,594.74%270.65M-3,382.00%-1.64M--140.52M--9.39M
Net cash flow
Beginning cash position 1,162.28%326.09M118.33%72.36M-3.56%45.65M126.93%71.51M1,162.28%326.09M51.50%25.83M-29.96%33.14M18.82%47.34M--31.51M--25.83M
Current changes in cash -174.71%-224.31M-89.96%29.41M288.15%26.71M-263.36%-25.85M-4,584.41%-254.58M3,318.96%300.25M1,463.48%292.94M-289.76%-14.19M--15.83M--5.68M
End cash Position -68.79%101.77M-68.79%101.77M118.33%72.36M-3.56%45.65M126.93%71.51M1,162.28%326.09M1,162.28%326.09M-29.96%33.14M--47.34M--31.51M
Free cash flow -123.58%-133.44M-55.00%-30.69M-56.10%-22.3M-388.88%-39.29M-134.40%-41.17M-56.77%-59.68M-22.89%-19.8M-196.49%-14.29M---8.04M---17.56M
Currency Unit USDUSDUSDUSDUSDUSDUSDUSDUSDUSD
Accounting Standards US-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAPUS-GAAP
Audit Opinions Unqualified Opinion--------Unqualified Opinion--------
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